This article provides a framework for the evaluation of mental health consumer/survivor organizations that consists of four main components: (a) participatory processes, (b) conceptualization of the activities and outcomes at the individual and systems levels of these organizations, (c) the combination of quantitative and qualitative methods for examining activities and outcomes, and (d) dissemination and action. We assert that these components form a comprehensive and holistic framework for evaluating mental health consumer/survivor organizations; we illustrate how these components can be put into action through a case study of four mental health consumer/survivor organizations in Ontario; and we reflect on the lessons that we have learned in conducting this evaluation.